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Departments of Surgery and Comparative Medicine, St. Louis University Medical Center, St. Louis, Missouri. Use the link below to share a full-text version of this article with your friends and colleagues. Learn more. In this study, the pitfalls of tumor measurement in the nude mouse were evaluated. Regarding intermethod variation, diameters of subcutaneous tumors in nude mice were expressed as length, area, and volume; tumor weights were also recorded.

These measurements were all compared to a reference standard: water displacement volume. Regarding interobserver variation, mean absolute difference among volumes determined by several investigators who measured the same tumors in living animals was determined. Regarding intraobserver variation, observers measured four separate masses in nude mice eight times each. The observers were prevented from realizing that the same animals were being repeatedly evaluated.

Volumes were compared in order to quantify the average variation that occurs when a single investigator repeatedly measures the same mass. Recommendations are made for future work employing tumor measurement. Volume 31 , Issue 4. The full text of this article hosted at iucr. Please check your for instructions on resetting your password.

If the address matches an existing you will receive an with instructions to retrieve your username. Journal of Surgical Oncology. David M. Louis, Missouri Search for more papers by this author. Louis, Missouri Department of Surgery, St. Louis, MO Search for more papers by this author. First published: April Tools Request permission Export citation Add to favorites Track citation. Share Share Give access Share full text access. Share full-text access. Please review our Terms and Conditions of Use and check box below to share full-text version of article.

Shareable Link Use the link below to share a full-text version of this article with your friends and colleagues. Abstract In this study, the pitfalls of tumor measurement in the nude mouse were evaluated. Citing Literature. Volume 31 , Issue 4 April s Related Information. Close Figure Viewer. Return to Figure. Download PDF.

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